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Confirmed |
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Isolation of Neisseria meningitidis from a usually sterile site including: |
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Blood |
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Cerebrospinal fluid |
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Synovial joint fluid |
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Pleural fluid |
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Pericardial fluid |
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Petechial or purpuric lesion (skin rash) |
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Presumptive |
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Gram-negative diplococcal organisms visualized by microscopy in any sterile fluid, such as cerebrospinal fluid, synovial fluid, or aspirate from a petechial or purpuric skin lesion |
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Probable |
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Positive antigen test for N. meningitidis in cerebrospinal fluid in the absence of a positive sterile site culture in the setting of a clinical illness consistent with meningococcal disease or clinical purpura fulminans in the absence of a positive blood culture. |
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Modified from American Academy of Pediatrics. Meningococcal infections. In Pickering LK, ed. 2000 Red Book: Report on the Committee on Infectious Diseases, 25th edition. Elk Grove Village, IL: American Academy of Pediatrics, 2000, p.396-401. |
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