Confirmed
Isolation of Neisseria meningitidis from a usually sterile site including:
Blood
Cerebrospinal fluid
Synovial joint fluid
Pleural fluid
Pericardial fluid
Petechial or purpuric lesion (skin rash)
Presumptive
Gram-negative diplococcal organisms visualized by microscopy in any sterile fluid, such as cerebrospinal fluid, synovial fluid, or aspirate from a petechial or purpuric skin lesion
Probable
Positive antigen test for N. meningitidis in cerebrospinal fluid in the absence of a positive sterile site culture in the setting of a clinical illness consistent with meningococcal disease or clinical purpura fulminans in the absence of a positive blood culture.
Modified from American Academy of Pediatrics. Meningococcal infections. In Pickering LK, ed. 2000 Red Book: Report on the Committee on Infectious Diseases, 25th edition. Elk Grove Village, IL: American Academy of Pediatrics, 2000, p.396-401.